guest stars: Martin Landau (Dr Alvin Kurtzweil) John Neville (Well-Manicured Man) Jeffrey DeMunn (Dr Ben Bronschweig) William B. Davis (Cigarette Smoking Man) Bruce Harwood (Byers) Dean Haglund (Langly) Tom Braidwood (Frohike) Don S. Williams (1st Elder) George Murdock (2nd Elder) Mitch Pileggi (Assistant Director Walter Skinner)

Co Stars: Blythe Danner (Assistant Director Jana Cassidy) Michael Krawic (2nd Paramedic) Paul Tuerpe (1st Paramedic) Vanessa Morley (young Samantha Mulder) (uncredited) Terry O'Quinn ( Special Agent Darius Michaud) Armin Mueller-Stahl ( Conrad Strughold) Lucas Black (Stevie) Michael Shamus Wiles (Black Haired Man) Gary Grubbs (Fire Captain Miles Cooles) Steve Rankin (Field Agent) Luis Beckford ( FBI Agent)

Thirty-seven thousand years ago, a deadly secret was buried in a cave in Texas. Now the secret has been unleashed. And its discovery may mean the end of all humanity. "The plague to end all plagues."

When a terrorist bomb destroys a building in Dallas, Texas, FBI Agents Fox Mulder and Dana Scully are drawn into a dangerous conspiracy surpassing anything they've ever encountered. With the dubious assistance of a paranoid doctor (Academy Award®-winner Martin Landau), Mulder and Scully risk their careers and their lives to hunt down a deadly virus which may be extraterrestrial in origin - and could destroy all life on earth. Their pursuit of truth pits them against the mysterious Syndicate, powerful men who will stop at nothing to keep their secrets safe, leading the agents from a cave in Texas, to the halls of the FBI, and finally to a secret installation in Antarctica which holds the greatest secret of all.

NOTE: It had a budget: $66 million. In the opening Weekend it took $30.138 million (2629 screens). and gross: $83.892 million.